Salvia Effects

Common Side Effects of Salvia Divinorum

Disclaimer:

None of the descriptions given on this site have been evaluated by the Food and Drug Administration (FDA). The methods of use for Salvia Divinorum and Salvorin A discussed on this site are not meant to diagnose, heal, cure, relieve or prevent any illnesses. All information on this site are the views of the individual writers who do not declare to be medical experts giving pharmaceutical advice. This site is strictly with the mission of providing views of the author. Effects of salvia may vary from each individual and quality of product.

Salvia divinorum may be known by many names such as: Shepherdess’s herb, diviner’s sage, seer’s sage, Sally-D to name a few; however, the one thing consistent when discussing salvia divinorum among users is its intense hallucinogenic effect. Salvia divinorum is a member of the mint family, or Lamiaceae, and is native to the Oaxaca Mountains in Mexico where it is sold as a legal hallucinogen.1 Salvia divinorum has been used for many generations by the Mazatec Indians for divination and healing in their rituals and was first discovered in the early 30’s by Jean Bassett Johnson, an American anthropologist from the University of Berkley.4

Salvia divinorum’s active ingredient that facilitates these intense and unequalled hallucinations is salvorin a. Salvorin A was discovered to be a KOR (kappa opiate receptor) agonist. The KOR is the part of the brain that controls human perception, such as one’s reality, and time and space perception. It is here where the true “magic” takes place.

For centuries the Mazatec’s have brewed dried leaves into a tea and consumed for visionary purposes during their ceremonies. They also rolled the soaked leaves into a quid and chewed it, or smoked it. Smoking salvia divinorum is still today the most effective way to enjoy salvia because the effects last longer with faster onset. Once smoked, either through a bong or pipe, it’s effects are felt in as little as 2 minutes and can last upwards of 30 to 45 minutes depending on quantity, and quality. To further understand the effects and intensity of Salvorin a, we have included a link to a test performed on primates by the US Department of Energy’s Brookhaven National Laboratory. https://www.sciencedaily.com/releases/2008/04/080428120701.htm Tests performed on primates showed when consumed, Salvorin a showed up in peak concentration in the cerebellum and visual cortex, which are responsible for motor function and vision. Onset occurred within 40 seconds of administration, 16 times faster than cocaine!2 Based on their results and published data from human consumption and experience with salvia divinorum, the scientists estimated that just 10 micrograms of salvia in the brain is all that is needed to cause psychoactive effects in humans. Brookhaven chemist Jacob Hooker said “Most people don’t find this class of drugs very pleasurable,” Hooker said. “So perhaps the main draw or reason for its appeal relates to the rapid onset and short duration of its effects, which are incredibly unique. The kinetics are often as important as the abused drug itself.”2  The Brookhaven team plans to continue research related to salvia divinorum’s abuse potential and they hope to develop radioactive tracers that can better probe the brain receptors which salvia binds to on the KOR receptors. Such studies could possibly lead to therapies for chronic pain and mood disorders in the near future. The reports of these studies are published online in the journal NeuroImage.

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In the journal titled “Drug and Alcohol Dependence, Use patterns and self-reported effects of Salvia divinorum: An internet-based survey, an anonymous internet survey among users on salvia divinorum related websites discovered this:

 “Participants (N = 500) were 92.6% male and 23.4 ± 8.7 (mean ± s.d.) years old. They had used a median of six times (range 1–250). 80.6% probably or definitely would use SD again. Most participants (92.6%) typically smoked or vaporized SD product. When smoked, the drug’s main effects were estimated to last 14.1 ± 12.8 (range 0.5–120) minutes. When asked to compare SD effects to other methods of altering consciousness, the most common answer was that SD was unique (38.4%). 25.8% reported persisting (≥24 h) positive effects (often described as increased sense of well-being) on at least one occasion. 4.4% reported persisting negative effects (most often anxiety).3 The anonymous survey discovered salvia divinorum is typically smoked, the side effects are typically brief, and persistent adverse effects are very rare. In addition to acute hallucinogenic effects, salvia divinorum may produce subacute increases in subjective well-being. Such a subacute effect would be unusual for a drug that is used non-medically, as withdrawal from other drugs typically either does not affect mood or causes dysphoria.”3

COMMON SIDE EFFECTS:

• Sweating
• Dizziness
• Lack of coordination
• Difficulty concentrating
• Confusion
• Slurred speech.

MORE UNCOMMON SIDE EFFECTS INCLUDE, but NOT limited to:

• Heightened senses, such as “hearing colors” or “seeing tastes”
• Inability to control body movements
• Feeling as if you are flying, or floating
• Visions of a woman-This would be the reasoning behind the name “shepherdess’s plant” or “Yierba de Maria’, the Mazatec’s believed this woman to be the incarnation of the Virgin Mary, while others believe this woman to be the ruler of the dimension the user visits under the influence
• Severe emotional changes
• Heaviness or lightness of body
• Distorted perception of time/space- some users have reported the feeling of visiting another dimension and probably encountering the woman
• Visual distortions such as bright lights, vivid colors and unusual shapes and patterns especially when eyes are closed
• Cartoon-like imagery
• Recollection of memories, such as revisiting places from childhood
• Sensations of motion, or being pulled, twisted, stretched, or flipped
• Talkativeness
• Merging with or becoming objects
• Distortion of time and space such as the feeling of being in several locations at once
• Out-of-body experiences
• Contact with entities or other dimensions
• Overall feeling of uneasiness
• Loss of contact with reality.4

References:

Wasson, R. (1963). NOTES ON THE PRESENT STATUS OF OLOLIUHQUI AND THE OTHER HALLUCINOGENS OF MEXICO. Botanical Museum Leaflets, Harvard University, 20(6), 161-193. Retrieved from http://www.jstor.org/stable/41762230

DOE/Brookhaven National Laboratory. (2008, April 28). Brain’s Reaction To Potent Hallucinogen Salvia Explored. ScienceDaily. Retrieved October 24, 2017 from www.sciencedaily.com/releases/2008/04/080428120701.htm

http://www.sciencedirect.com/science/article/pii/S0376871610001717

https://www.medicalnewstoday.com/articles/309735.php

Image from: ttps://ryky.deviantart.com/art/The-Time-Space-634786082